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EJNMMI Radiopharmacy and Chemistry
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  1. The Editorial Board of EJNMMI Radiopharmacy and Chemistry releases a biannual highlight commentary to update the readership on trends in the field of radiopharmaceutical development.

    Authors: Peter JH. Scott, Ivan Penuelas, Ana Rey, Silvio Aime, Pillai M.R. Ambikalmajan, Ines Farinha Antunes, Frederik Cleeren, Zhaofei Liu, Beverley Ellis, Maryke Kahts, Fany Pricile Ekoume, Ivis F. Chaple, Emerson Bernardes, Martin Behe, Ya-Yao Huang, Renata Mikolajczak…
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:67
    Content type: Review Published on:

  2. A novel positron emission tomography (PET) imaging tracer, [18F] SynVesT-1, targeting synaptic vesicle glycoprotein 2 (SV2A), has been developed to meet clinical demand. Utilizing the Trasis AllinOne-36 (AIO) mod...

    Authors: Lijuan Chen, Xiaochen Li, Yao Ge, Huiqiang Li, Ruili Li, Xiaosheng Song, Jianfei Liang, Weifeng Zhang, Xiaona Li, Xiaoqi Wang, Yunjuan Wang, Yaping Wu, Yan Bai and Meiyun Wang
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:66
    Content type: Research article Published on:

  3. Radiopharmaceuticals have been considered a special group of medicines in Europe since 1989. The use of radiopharmaceuticals that have marketing authorization should always be the first option in clinical use,...

    Authors: Estrella Moya, Celia Cerrato, Luis Miguel Bedoya and José Antonio Guerra
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:64
    Content type: Review Published on:

  4. Selection of the most promising radiotracer candidates for radiolabeling is a difficult step in the development of radiotracer pharmaceuticals, especially for the brain. Mass spectrometry (MS) is an alternativ...

    Authors: Laurent Galineau, Emmanuelle Claude, Zuhal Gulhan, Sylvie Bodard, Sophie Sérrière, Camille Dupuy, Jérémy Monteiro, Adeline Oury, Priscila Bertevello, Gabrielle Chicheri, Johnny Vercouillie, Lydie Nadal-Desbarats, Sylvie Chalon, Antoine Lefèvre and Patrick Emond
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:63
    Content type: Research article Published on:

  5. Prostate Cancer (PCa) is the second most diagnosed urological cancer among men worldwide. Conventional methods used for diagnosis of PCa have several pitfalls which include lack of sensitivity and specificity....

    Authors: Jubilee Andrew, Amanda-Lee Ezra-Manicum and Bwalya Angel Witika
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:62
    Content type: Review Published on:

  6. This study aimed to develop a novel positron emission tomography (PET) tracer, [68Ga]Ga-TD-01, for CXCR4 imaging. To achieve this goal, the molecular scaffold of TIQ15 was tuned by conjugation with the DOTA chela...

    Authors: Piyapan Suwattananuruk, Sukanya Yaset, Chanisa Chotipanich, Angel Moldes-Anaya, Rune Sundset, Rodrigo Berzaghi, Stine Figenschau, Sandra Claes, Dominique Schols, Pornchai Rojsitthisak, Mathias Kranz and Opa Vajragupta
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:61
    Content type: Research article Published on:

  7. In recent years, targeted alpha therapy has gained importance in the clinics, and in particular, the alpha-emitter 225Ac plays a fundamental role in this clinical development. Nevertheless, depending on the chela...

    Authors: Santiago Andrés Brühlmann, Martin Walther, Magdalena Kerstin Blei, Constantin Mamat, Klaus Kopka, Robert Freudenberg and Martin Kreller
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:60
    Content type: Research article Published on:

  8. Convenient therapeutic protocols for hepatocellular carcinoma (HCC) are often ineffective due to late diagnosis and high tumor heterogeneity, leading to poor long-term outcomes. However, recently performed stu...

    Authors: Nasrin Abbasi Gharibkandi, Kamil Wawrowicz, Rafał Walczak, Agnieszka Majkowska-Pilip, Mateusz Wierzbicki and Aleksander Bilewicz
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:59
    Content type: Research article Published on:

  9. The cysteine-aspartic acid protease caspase-3 is recognized as the main executioner of apoptosis in cells responding to specific extrinsic and intrinsic stimuli. Caspase-3 represents an interesting biomarker t...

    Authors: Louis Lauwerys, Lucas Beroske, Angelo Solania, Christel Vangestel, Alan Miranda, Nele Van Giel, Karuna Adhikari, Anne-Marie Lambeir, Leonie wyffels, Dennis Wolan, Pieter Van der Veken and Filipe Elvas
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:58
    Content type: Research article Published on:

  10. The integration of positron emission tomography (PET) and magnetic resonance imaging (MRI) holds promise for advancing diagnostic imaging capabilities. The METRICS project aims to develop cyclotron-driven prod...

    Authors: Francesca Porto, Sara Cisternino, Emiliano Cazzola, Giorgia Speltri, Liliana Mou, Alessandra Boschi, Lorenza Marvelli, Giovanni Di Domenico, Antonella Pagnoni, Lucia De Dominicis, Irene Calliari, Claudio Gennari, Licia Uccelli, Gaia Pupillo, Giancarlo Gorgoni, Juan Esposito…
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:57
    Content type: Research article Published on:

  11. Currently, the synthesis pathway of metal nuclide-labeled radiopharmaceuticals is mainly divided into two steps: first, connecting the chelator with the target molecule, and second, labeling the metal nuclide ...

    Authors: Xiaobei Zheng, Shuai Xue, Zhongqi Zhao, Shuxin Jin, Shuhua He, Lina Jia, Zheng Li, Christian Vanhove, Filip De Vos, Zijun Kuang, Tiantian Wang, Sara Neyt, Lan Zhang and Xiao Li
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:56
    Content type: Research article Published on:

  12. Fibroblast activation protein (FAP), a transmembrane serine protease overexpressed by cancer-associated fibroblasts in the tumor stroma, is an interesting biomarker for targeted radionuclide theranostics. FAP-...

    Authors: Circe D. van der Heide, Hanyue Ma, Mark W.H. Hoorens, Joana D. Campeiro, Debra C. Stuurman, Corrina M.A. de Ridder, Yann Seimbille and Simone U. Dalm
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:55
    Content type: Research article Published on:

  13. Radiofluorination of single domain antibodies (sdAbs) via N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB) has shown to be a promising strategy in the development of sdAb-based PET tracers. While automation of the...

    Authors: Herlinde Dierick, Laurent Navarro, Hannelore Ceuppens, Thomas Ertveldt, Ana Rita Pombo Antunes, Marleen Keyaerts, Nick Devoogdt, Karine Breckpot, Matthias D’Huyvetter, Tony Lahoutte, Vicky Caveliers and Jessica Bridoux
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:54
    Content type: Research article Published on:

  14. 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) is commonly used for diagnosis of dementia because brain glucose metabolism reflects neuronal activity. However, as [18F]FDG is an analogue of glucose, accumulation of t...

    Authors: Jun Toyohara, Tetsuro Tago and Muneyuki Sakata
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:53
    Content type: Research article Published on:

  15. Glioblastoma (GBM), is the most fatal form of brain cancer, with a high tendency for recurrence despite combined treatments including surgery, radiotherapy, and chemotherapy with temozolomide. The C-X-C chemok...

    Authors: Anthony Waked, Melissa Crabbé, Virginie Neirinckx, Sunay Rodriguez Pérez, Jasmien Wellens, Bernard Rogister, M. Abderrafi Benotmane and Koen Vermeulen
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:52
    Content type: Research article Published on:

  16. 4-[18F]fluorobenzyl-triphenylphosphonium ([18F]FBnTP) is a lipophilic cation PET tracer. The cellular uptake of [18F]FBnTP is correlated with oxidative phosphorylation by mitochondria, which has been associated w...

    Authors: Mai Lin, Cong-Dat Pham, Robert T. Ta and H. Charles Manning
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:51
    Content type: Research article Published on:

  17. In the last decade the development of new PSMA-ligand based radiopharmaceuticals for the imaging and therapy of prostate cancer has been a highly active and important area of research. The most promising deriv...

    Authors: Marco Nicola Iannone, Silvia Valtorta, Stefano Stucchi, Stefano Altomonte, Elia Anna Turolla, Elisa Vino, Paolo Rainone, Valentina Zecca, Alessia Lo Dico, Marco Maspero, Mariangela Figini, Matteo Bellone, Samuele Ciceri, Diego Colombo, Clizia Chinello, Lisa Pagani…
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:50
    Content type: Research article Published on:

  18. Infection remains a major cause of morbidity and mortality, regardless of advances in antimicrobial therapy and improved knowledge of microorganisms. With the major global threat posed by antimicrobial resista...

    Authors: Maryke Kahts, Beverley Summers, Aadil Gutta, Wilfrid Pilloy and Thomas Ebenhan
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:49
    Content type: Review Published on:

  19. Prostate cancer is a common cancer among men worldwide that has a very poor prognosis, especially when it progresses to metastatic castration-resistant prostate cancer (mCRPC). Therefore, novel therapeutic age...

    Authors: Hiroyuki Suzuki, Kento Kannaka, Mizuki Hirayama, Tomoki Yamashita, Yuta Kaizuka, Ryota Kobayashi, Takahiro Yasuda, Kazuhiro Takahashi and Tomoya Uehara
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:48
    Content type: Research article Published on:

  20. Trans-cyclooctenes (TCOs) are highly strained alkenes with remarkable reactivity towards tetrazines (Tzs) in inverse electron-demand Diels–Alder reactions. Since their discovery as bioorthogonal reaction partners...

    Authors: Karuna Adhikari, Maarten Vanermen, Gustavo Da Silva, Tim Van den Wyngaert, Koen Augustyns and Filipe Elvas
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:47
    Content type: Review Published on:

  21. Signal transducer and activator of transcription 3 (STAT3) is a protein that regulates cell proliferation and differentiation, and it is attracting attention as a new index for evaluating cancer pathophysiolog...

    Authors: Anna Miyazaki, Yasukazu Kanai, Keita Wakamori, Serina Mizuguchi, Mikiya Futatsugi, Fuko Hirano, Naoya Kondo and Takashi Temma
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:46
    Content type: Research article Published on:

  22. Histone deacetylase 6 (HDAC6) is an emerging target for the treatment and diagnosis of proteinopathies. [18F]FSW-100 was recently developed as a promising brain-penetrating radioligand for HDAC6 PET imaging and t...

    Authors: Tetsuro Tago and Jun Toyohara
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:45
    Content type: Research article Published on:

  23. Integrating radioactive and optical imaging techniques can facilitate the prognosis and surgical guidance for cancer patients. Using a single dual-labeled tracer ensures consistency in both imaging modalities....

    Authors: Dylan Chapeau, Savanne Beekman, Maryana Handula, Erika Murce, Corrina de Ridder, Debra Stuurman and Yann Seimbille
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:44
    Content type: Research article Published on:

  24. A significant challenge in cancer therapy lies in eradicating hidden disseminated tumor cells. Within Nuclear Medicine, Targeted Alpha Therapy is a promising approach for cancer treatment tackling disseminated...

    Authors: Chiara Timperanza, Holger Jensen, Ellinor Hansson, Tom Bäck, Sture Lindegren and Emma Aneheim
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:43
    Content type: Research article Published on:

  25. The Editorial Board of EJNMMI Radiopharmacy and Chemistry releases a biannual highlight commentary to update the readership on trends in the field of radiopharmaceutical development.

    Authors: Jun Toyohara, Danielle Vugts, Oliver C. Kiss, Sergio Todde, Xiang-Guo Li, Zhibo Liu, Zhi Yang, Nic Gillings, Emiliano Cazzola, Wiktor Szymanski, Nick van der Meulen, Raymond Reilly, Carlotta Taddei, Ralf Schirrmacher, Zijing Li, Yohannes Jorge Lagebo…
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:42
    Content type: Review Published on:

  26. Determination of the functional liver mass is important in a variety of clinical settings including liver surgery and transplantation. [99mTc]Tc-diethylenetriamine-pentaacetic acid galactosyl human serum albumin ...

    Authors: Maximilian A. Zierke, Christine Rangger, Kimia Samadikhah, Marlene Panzer, Stefanie Dichtl, Nikolas Hörmann, Doris Wilflingseder, Andreas M. Schmid and Roland Haubner
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:41
    Content type: Research article Published on:

  27. During the previous two decades, PET imaging of biopharmaceuticals radiolabeled with zirconium-89 has become a consistent tool in preclinical and clinical drug development and patient selection, primarily due ...

    Authors: Thomas Erik Wuensche, Serge Lyashchenko, Guus A. M. S. van Dongen and Danielle Vugts
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:40
    Content type: Review Published on:

  28. Automated [89Zr]Zr-radiolabeling processes have the potential to streamline the production of [89Zr]Zr-labelled PET imaging agents. Most radiolabeling protocols use [89Zr][Zr(ox)4]4− as the starting material and ...

    Authors: Asif Noor, Peter D. Roselt, Emily R. McGowan, Stan Poniger, Michael P. Wheatcroft and Paul S. Donnelly
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:39
    Content type: Research article Published on:

  29. Positron emission tomography (PET) is a highly sensitive method that provides fine resolution images, useful in the field of clinical diagnostics. In this context, Zirconium-89 (89Zr)-based imaging agents have re...

    Authors: Valentina Albanese, Chiara Roccatello, Salvatore Pacifico, Remo Guerrini, Delia Preti, Silvia Gentili, Matteo Tegoni, Maurizio Remelli, Denise Bellotti, Jonathan Amico, Giancarlo Gorgoni and Emiliano Cazzola
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:38
    Content type: Research article Published on:

  30. Radiation nanomedicines are nanoparticles labeled with radionuclides that emit α- or β-particles or Auger electrons for cancer treatment. We describe here our 15 years scientific journey studying locally-admin...

    Authors: Raymond M. Reilly, Constantine J. Georgiou, Madeline K. Brown and Zhongli Cai
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:37
    Content type: Review Published on:

  31. In recent years, fibroblast activating protein (FAP), a biomarker overexpressed by cancer-associated fibroblasts, has emerged as one of the most promising biomarkers in oncology. Similarly, FAP overexpression ...

    Authors: Alessandra Boschi, Luca Urso, Licia Uccelli, Petra Martini and Luca Filippi
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:36
    Content type: Review Published on:

  32. Parkinson's disease is a neurodegenerative disorder that is characterized by a degeneration of the dopaminergic system. Dopamine transporter (DAT) positron emission tomography (PET) imaging has emerged as a po...

    Authors: Mélodie Ferrat, Mohammad M. Moein, Carmen Cananau, Tetyana Tegnebratt, Paul Saliba, Fredrik Norman, Carsten Steiger, Klas Bratteby, Erik Samén, Kenneth Dahl and Thuy A. Tran
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:35
    Content type: Methodology Published on:

  33. 6-Bromo-7-[11C]methylpurine ([11C]BMP) is a radiotracer for positron emission tomography (PET) to measure multidrug resistance-associated protein 1 (MRP1) transport activity in different tissues. Previously repor...

    Authors: Severin Mairinger, Matthias Jackwerth, Ondřej Soukup, Matthias Blaickner, Clemens Decristoforo, Lukas Nics, Jens Pahnke, Marcus Hacker, Markus Zeitlinger and Oliver Langer
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:34
    Content type: Research article Published on:

  34. The aim of this study was to prepare a novel 68Ga-labeled pH (low) insertion peptide (pHLIP)-like peptide, YJL-4, and determine its value for the early diagnosis of triple-negative breast cancer (TNBC) via in viv...

    Authors: YueHua Chen, ShuangShuang Song, YanQin Sun, FengYu Wu, GuangJie Yang, ZhenGuang Wang and MingMing Yu
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:33
    Content type: Research article Published on:

  35. Megalin (LRP2 receptor) mediates the endocytosis of radiolabeled peptides into proximal tubular kidney cells, which may cause nephrotoxicity due to the accumulation of a radioactive tracer. The study aimed to ...

    Authors: Anna Durinova, Lucie Smutna, Pavel Barta, Rajamanikkam Kamaraj, Tomas Smutny, Bernhard Schmierer, Petr Pavek and Frantisek Trejtnar
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:32
    Content type: Research article Published on:

  36. Steps have been taken by pharmaceutical companies to obtain marketing authorisation of PSMA ligands in the European Union. Since December 2022, Locametz® (PSMA-11, gozetotide) is licensed as kit for manual rad...

    Authors: Elke A. van Brandwijk, Else A. Aalbersberg, Arman S. Hosseini, Alwin D. R. Huitema and Jeroen J. M. A. Hendrikx
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:31
    Content type: Research article Published on:

  37. Radionuclide molecular imaging can be used to visualize the expression levels of molecular targets. Affibody molecules, small and high affinity non-immunoglobulin scaffold-based proteins, have demonstrated pro...

    Authors: Maryam Oroujeni, Matilda Carlqvist, Eva Ryer, Anna Orlova, Vladimir Tolmachev and Fredrik Y. Frejd
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:30
    Content type: Research article Published on:

  38. The alpha emitter astatine-211 (211At) is garnering attention as a novel targeted alpha therapy for patients with refractory thyroid cancer resistant to conventional therapy using beta emitter radioiodine (131I)....

    Authors: Sadahiro Naka, Kazuhiro Ooe, Yoshifumi Shirakami, Kenta Kurimoto, Toshihiro Sakai, Kazuhiro Takahashi, Atsushi Toyoshima, Yang Wang, Hiromitsu Haba, Hiroki Kato, Noriyuki Tomiyama and Tadashi Watabe
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:29
    Content type: Research article Published on:

  39. (S)-[18F]FETrp is a promising PET radiotracer for imaging IDO1 activity, one of the main enzymes involved in the tryptophan metabolism that plays a key role in several diseases including cancers. To date, the rad...

    Authors: Aurélie Maisonial-Besset, David Kryza, Klaus Kopka, Sophie Levesque, Emmanuel Moreau, Barbara Wenzel and Jean-Michel Chezal
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:28
    Content type: Research article Published on:

  40. Tau pathology plays a crucial role in neurodegeneration diseases including Alzheimer’s disease (AD) and non-AD diseases such as progressive supranuclear palsy. Tau positron emission tomography (PET) is an in-v...

    Authors: Kun-Ju Lin, Shao-Yi Huang, Kuo-Lun Huang, Chin-Chang Huang and Ing-Tsung Hsiao
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:27
    Content type: Research article Published on:

  41. To investigate the capacity of 99mTc-labeled 1-thio-β-D-glucose (1-TG) and 5-thio-D-glucose (5-TG) to act as a marker for glucose consumption in tumor cells in vivo as well as to evaluate the biodistribution of 1...

    Authors: Fabian Muehlberg, Konrad Mohnike, Oliver S. Grosser, Maciej Pech, Juergen Goldschmidt, Karl-Heinz Smalla, Ricarda Seidensticker, Muzaffer Reha Ümütlü, Sinan Deniz, Jens Ricke, Ingo G. Steffen, Osman Öcal and Max Seidensticker
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:26
    Content type: Research article Published on:

  42. The urgent demand for innovative theranostic strategies to combat bacterial resistance to antibiotics is evident, with substantial implications for global health. Rapid diagnosis of life-threatening infections...

    Authors: Jyotsna Bhatt Mitra, Saurav Chatterjee, Anuj Kumar, Elina Khatoon, Ashok Chandak, Sutapa Rakshit, Anupam Bandyopadhyay and Archana Mukherjee
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:25
    Content type: Research article Published on:

  43. Production of [11C]CH4 from gas targets is notorious for weak performance with respect to yield, especially when using high beam currents. Post-target conversion of [11C]CO2 to [11C]CH4 is a widely used roundabou...

    Authors: Semi Helin, Johan Rajander, Jussi Aromaa, Eveliina Arponen, Jatta S. Helin and Olof Solin
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:24
    Content type: Research article Published on:

  44. Both in clinical routine and in preclinical research, the established standard procedure for the final purification of radiometal-labeled peptide radiopharmaceuticals is cartridge-based reversed-phase (RP) sol...

    Authors: Sebastian Martin, Lennard Wendlinger, Alexandra Litvinenko, Radmila Faizova and Margret Schottelius
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:23
    Content type: Methodology Published on:

  46. The brain is a challenging target for antibody-based positron emission tomography (immunoPET) imaging due to the restricted access of antibody-based ligands through the blood–brain barrier (BBB). To overcome t...

    Authors: Eva Schlein, Johanna Rokka, Luke R. Odell, Sara Lopes van den Broek, Matthias M. Herth, Umberto M. Battisti, Stina Syvänen, Dag Sehlin and Jonas Eriksson
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:21
    Content type: Research article Published on:

  47. Siderophores are small iron-binding molecules produced by microorganisms to facilitate iron acquisition from the environment. Radiolabelled siderophores offer a promising solution for infection imaging, as the...

    Authors: Kristyna Krasulova, Barbora Neuzilova, Katerina Dvorakova Bendova, Zbynek Novy, Miroslav Popper, Marian Hajduch and Milos Petrik
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:20
    Content type: Research article Published on:

  48. Heat shock proteins (HSPs) are present throughout the brain. They function as molecular chaperones, meaning they help with the folding and unfolding of large protein complexes. These chaperones are vital in th...

    Authors: Takayuki Sakai, Aya Ogata, Hiroshi Ikenuma, Takashi Yamada, Saori Hattori, Junichiro Abe, Shinichi Imamura, Masanori Ichise, Mari Tada, Akiyoshi Kakita, Hiroko Koyama, Masaaki Suzuki, Takashi Kato, Kengo Ito and Yasuyuki Kimura
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:19
    Content type: Research article Published on:

  49. Radiohybrid PSMA-targeted ligands (rhPSMA) have been introduced as a novel platform for theranostic applications. Among a variety of rhPSMA-ligands developed for radioligand therapy, two stereoisomers [177Lu]Lu-r...

    Authors: Alexander Wurzer, Francesco De Rose, Sebastian Fischer, Markus Schwaiger, Wolfgang Weber, Stephan Nekolla, Hans-Jürgen Wester, Matthias Eiber and Calogero D’Alessandria
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:18
    Content type: Research article Published on:

  50. L-type amino acid transporter 1 (LAT1) is overexpressed in various cancers; therefore, radiohalogen-labeled amino acid derivatives targeting LAT1 have emerged as promising candidates for cancer radiotheranosti...

    Authors: Yuta Kaizuka, Hiroyuki Suzuki, Tadashi Watabe, Kazuhiro Ooe, Atsushi Toyoshima, Kazuhiro Takahashi, Koichi Sawada, Takashi Iimori, Yoshitada Masuda, Takashi Uno, Kento Kannaka and Tomoya Uehara
    Citation: EJNMMI Radiopharmacy and Chemistry 2024 9:17
    Content type: Research article Published on:

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