Thematic Series

Regulatory

Radiopharmaceuticals are a unique and highly regulated class of medicinal products. Their preparation is governed by both radiation protection and pharmaceutical regulations. The latter, originally designed for standard non-radioactive drugs, has often failed to fully acknowledge the unique nature of radiopharmaceuticals. This lack of understanding by regulatory authorities worldwide is further complicated by significant differences between various countries and regions. As a result, scientific societies have been actively involved in establishing appropriate standards and procedures. These efforts aim to guide the radiopharmaceutical community through the often-intricate set of rules and requirements, and to suggest modifications to legislation and associated guidelines.

This new collection of EJNMMI Radiopharmacy and Chemistry has two primary goals: (1) to encourage the publication of new articles on any topic related to guidelines, legislation, regulations, or recommendations that could impact the preparation of radiopharmaceuticals, including translational aspects such as clinical, preclinical or toxicological studies; and (2) to serve as a central repository for all articles and guidelines published by EANM, IAEA or other contributors in this field, making them readily accessible to the radiopharmaceutical community.

Please click here to see all articles of the collection.

Sergio Todde
Department of Medicine and Surgery – University of Milano-Bicocca / Tecnomed Foundation, Monza (Italy)

Marianne Patt
Section Pharmaceutical Radiochemistry, Department for Nuclear Medicine, University Hospital Augsburg, Germany

Iván Peñuelas
Radiopharmacy Unit, Department of Nuclear Medicine, University Hospital of Navarra, Pamplona, Spain

Radiopharmacy practices in Africa

EJNMMI Radiopharmacy and Chemistry aims to support radiopharmacy field in Africa as it is clear that radiopharmacy is growing up in African countries in parallel with the progress in nuclear medicine field. Many African groups are working in different radiopharmacy fields, so we encourage all African working groups to submit their new research and review articles on the following topics: radiopharmacy research and development, radioisotopes production and separation, SPECT radiopharmaceuticals, PET radiopharmaceuticals, therapeutic radiopharmaceuticals, radiopharmacy practices and supply chains, feasibility studies, quality control studies, radiopharmacy education and training, radiopharmacy safety and regulations, advanced research on radiopharmaceutical chemistry…etc. Here we invite you to use this opportunity of publishing your work in this high level reputable radiopharmacy journal.

Please click here to see all articles of the collection.

Dr.  Naoual Bentaleb
National Center for Nuclear Energy, Science and Technology-CNESTEN
Rabat, Morocco

Mr. Yohannes Jorge Lagebo
Senior Radiopharmacist & Assistant Professor Of Nuclear Medicine
School of Medicine (SOM),College of Health Sciences (CHS), Addis Ababa University (AAU), Addis Ababa-Ethiopia

Dr. Tamer Sakr
Radioactive Isotopes and Generators Department, Hot Labs. Center, Egyptian Atomic Energy Authority, Cairo, Egypt.

Best practices in radiopharmaceutical chemistry

Radiopharmaceutical chemistry traditionally is a field in which research and development play an important role on one hand, but where on the other hand standardization and GMP-regulation are becoming increasingly important. In addition, there is a trend towards automated synthesis / radiolabeling procedures. More recently, labeling kits are gaining more interest. Factors such as specific activity of the radionuclide, (radio)chemical purity, chelator design, radiochemical yield, molar activity play an important role in optimizing of the radiolabeling or radiosynthesis process. The aim of this thematic series is to provide a comprehensive overview of the background but also the practical aspects and pitfalls of the radiolabeling or radiosynthesis procedures for various, commonly used, radionuclides and radiopharmaceuticals. 

Please click here to see all articles of the collection.

Dr Peter Laverman
Department of Medical Imaging, Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands

Dr Lars Perk
Radboud Translational Medicine, Radboud University Medical Center, Nijmegen, The Netherlands