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Correction: Physiologically based radiopharmacokinetic (PBRPK) modeling to simulate and analyze radiopharmaceutical therapies: studies of non-linearities, multi-bolus injections, and albumin binding

EJNMMI Radiopharmacy and Chemistry volume 9, Article number: 22 (2024) Cite this article

The Original Article was published on 22 January 2024


Correction: EJNMMI Radiopharmacy and Chemistry (2024) 9:6 https://doi.org/10.1186/s41181-023-00236-w

In the original publication of the article, inaccuracies were identified in Figures 3 and 7 due to an incorrect application of S values in the dose calculations. The S values, which should vary with tumor volume to accurately represent dose distribution, were mistakenly kept constant.

Upon review, the authors have corrected this error and recalculated the doses with varying 1/s values as they should proportionally change with tumor sizes (volumes). Below is a Table 1 of the corrected S values and their corresponding tumor volumes:

Table 1 Corrected S values and corresponding tumor volumes
Full size table

These errors also affected figures 3 and 7. The incorrect and correct figures are shown in this correction article. The corrected figures show that with increasing volumes the distributions are minimally altered; all other figures and conclusions remain intact.


Incorrect figure 3

figure a

Incorrect figure 7

figure b

Correct figure 3

figure c

Correct figure 7

figure d

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Authors and Affiliations

  1. School of Biomedical Engineering, University of British Columbia, Vancouver, BC, Canada

    Ali Fele‑Paranj & Arman Rahmim

  2. Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada

    Ali Fele‑Paranj, Carlos Uribe & Arman Rahmim

  3. Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, USA

    Babak Saboury

  4. Department of Functional Imaging, BC Cancer, Vancouver, BC, Canada

    Carlos Uribe

  5. Department of Radiology, University of British Columbia, Vancouver, BC, Canada

    Carlos Uribe & Arman Rahmim

Authors
  1. Ali Fele‑Paranj
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  2. Babak Saboury
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  3. Carlos Uribe
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  4. Arman Rahmim
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Corresponding author

Correspondence to Arman Rahmim.

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Fele‑Paranj, A., Saboury, B., Uribe, C. et al. Correction: Physiologically based radiopharmacokinetic (PBRPK) modeling to simulate and analyze radiopharmaceutical therapies: studies of non-linearities, multi-bolus injections, and albumin binding. EJNMMI radiopharm. chem. 9, 22 (2024). https://doi.org/10.1186/s41181-024-00251-5

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  • DOI: https://doi.org/10.1186/s41181-024-00251-5