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EJNMMI Radiopharmacy and Chemistry
Fig. 3 | EJNMMI Radiopharmacy and Chemistry

Fig. 3

From: Optimization and scale up of production of the PSMA imaging agent [18F]AlF-P16-093 on a custom automated radiosynthesis platform

Fig. 3

Effects of starting P16-093 and mole ratio of P16-093: AlCl3·6H2O on yield using optimized PiBOX reaction conditions. N = 3–4 for each data point. *P < 0.05; **P < 0.02; ***P < 0.0001. The bar graph represents results from a single experiment using the same conditions and reagents as the 4:1 mol ratio (80 nmol P16-093) runs except that the 18F-rinse volume was diluted with ultrapure water and sampled so that ~ 1/10 of the original 18F-rinse activity and volume was used for PiBOX

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