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EJNMMI Radiopharmacy and Chemistry

Table 1 Labelling of Affibody molecules with 99mTc and in vitro stability

From: Comparison of approaches for increasing affinity of affibody molecules for imaging of B7-H3: dimerization and affinity maturation

 

Radiochemical yield, %

Stability in PBS, 37 °C, 4 h

ZAC12*-ZAC12*-GGGC

97.4 ± 1.1

94.5 ± 0.2

ZAC12*-ZTaq_3-GGGC

97.6 ± 1.5

94.3 ± 1.5

SYNT-179

99.3 ± 0.4

95 ± 1

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