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EJNMMI Radiopharmacy and Chemistry
Fig. 9 | EJNMMI Radiopharmacy and Chemistry

Fig. 9

From: Comparison of approaches for increasing affinity of affibody molecules for imaging of B7-H3: dimerization and affinity maturation

Fig. 9

Uptake of (A) [99mTc]Tc-ZAC12*-ZAC12*-GGGC and (B) [99mTc]SYNT-179 on SKOV-3 (B7-H3-positive) xenografts at 4 h after injection. B7-H3 was blocked with pre-injection of 600 µg of Affibody molecule 40 min before injection of the radioconjugate. Data are expressed as %ID/g and are averages from four mice ± SD. Asterisk (*) marks significant (p < 0.05) difference

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