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EJNMMI Radiopharmacy and Chemistry
Fig. 10 | EJNMMI Radiopharmacy and Chemistry

Fig. 10

From: Comparison of approaches for increasing affinity of affibody molecules for imaging of B7-H3: dimerization and affinity maturation

Fig. 10

Imaging of [99mTc]Tc-ZAC12*-ZAC12*-GGGC in BALB/C nu/nu mice bearing (A) B7-H3-negative Ramos xenografts and (B) B7-H3-positive SKOV3 xenografts 4 h after injection. 7.8 µg of labelled Affibody molecule (14 MBq, 100 µL in PBS) was injected into the tail vein. Arrows point at tumours (T). The animals were imaged simultaneously. Linear relative scale (arbitrary units normalized to a maximum count rate) was adjusted to visualize B7-H3-positive SKOV-3 xenograft

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