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Table 2 The uptake of [18F]Florzolotau in each organ at different time points

From: Human biodistribution and radiation dosimetry for the tau tracer [18F]Florzolotau in healthy subjects

Organs

15 min

65 min

125 min

245 min

Brain

2.75 ± 0.33

1.08 ± 0.18

0.86 ± 0.16

0.54 ± 0.11

Thyroid

0.13 ± 0.04

0.07 ± 0.02

0.05 ± 0.01

0.03 ± 0.01

Heart wall

1.30 ± 0.68

0.65 ± 0.43

0.53 ± 0.37

0.39 ± 0.32

Lung

4.40 ± 2.79

2.73 ± 1.41

2.22 ± 1.02

1.52 ± 0.65

Liver

29.36 ± 5.18

26.72 ± 4.11

18.88 ± 4.50

11.63 ± 3.65

Gallbladder

0.81 ± 0.53

3.89 ± 5.42

4.96 ± 4.78

1.51 ± 1.46

Stomach

1.44 ± 0.74

1.56 ± 0.92

0.98 ± 0.51

0.40 ± 0.33

Intestine

8.44 ± 2.04

18.75 ± 6.02

31.33 ± 10.43

45.66 ± 7.22

Spleen

0.38 ± 0.28

0.25 ± 0.30

0.18 ± 0.24

0.10 ± 0.12

Kidney

3.26 ± 1.11

2.05 ± 0.73

1.64 ± 0.59

0.94 ± 0.38

Bladder

0.74 ± 0.17

1.61 ± 0.31

0.46 ± 0.37

0.14 ± 0.11

Testis

0.14 ± 0.05

0.13 ± 0.05

0.12 ± 0.05

0.10 ± 0.04

Uterus

0.26 ± 0.05

0.20 ± 0.06

0.18 ± 0.06

0.15 ± 0.08

  1. 15 min refers to the average from 10 to 20 min after injection, 65 min refers to the average from 60 to 70 min after injection, and so forth and so on. Units: percentage of injection dose (%ID/organ) represented in mean ± standard deviation