Fig. 2
From: Neopentyl glycol-based radiohalogen-labeled amino acid derivatives for cancer radiotheranostics
Cellular uptake and release of [211At]At-NpGT, [125I]I-NpGT and [18F]F-NpGT from C6 cells. a Time-course study of uptake. b Time-course study of extracellular release. The Y-axis shows the percentage release of each agent. c Inhibition of each agent’s uptake with amino acids and a LAT1-selective inhibitor (1 mM). The Y-axis shows the percentage of the control. The inhibitors were as follows Tyr = L-tyrosine; BCH = 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid; MeAIB = α-methyl-aminoisobutyric acid; AMT = α-methyl-L-tyrosine