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EJNMMI Radiopharmacy and Chemistry

Table 1 Radiosynthesis of [18F]ADPM06 using the automated 18F-labeling synthesizer

From: Automated radiosynthesis and in vivo evaluation of 18F-labeled analog of the photosensitizer ADPM06 for planning photodynamic therapy

ADPM06 (μmol)

SnCl4 (μmol)

SnCl4/ADPM06

RCY (%)

RCP (%)

0.2

100

500:1

4.4

> 99

0.2

200

1000:1

11 ± 7.9a

> 98

0.4

200

500:1

13 ± 2.7b

> 99

0.4

300

750:1

37

> 95

0.8

400

500:1

14

> 99

  1. aMean ± SD (n = 3)
  2. bMean ± SD (n = 5)
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