Table 4 Results of [177Lu]Lu-FAPI-46
From: Optimization of 177Lu-labelling of DOTA-TOC, PSMA-I&T and FAPI-46 for clinical application
Synthesis no | Starting activity (MBq) | Amount of FAPI-46 (µg/GBq) | Balanced radiochem. yield (%) | Radiochem. purity (%) radio-HPLC | Radiochem. purity (%) TLC |
|---|---|---|---|---|---|
1 | 7914 | 12.6 | 85 | 99.8 | 99.8 |
2 | 7618 | 17.1 | 87 | 99.3 | 99.7 |
3 | 8279 | 9.7 | 95 | 99.8 | 100.0 |
4 | 8087 | 12.4 | 96 | 99.4 | 99.9 |
5 | 6749 | 11.9 | 94 | 99.0 | 99.9 |