Table 3 Results of [177Lu]Lu-PSMA-I&T
From: Optimization of 177Lu-labelling of DOTA-TOC, PSMA-I&T and FAPI-46 for clinical application
Synthesis no | Starting activity (MBq) | Amount of PSMA-I&T (µg/GBq) | Balanced radiochem. yield (%) | Radiochem. purity (%) radio-HPLC | Radiochem. purity (%) TLC |
|---|---|---|---|---|---|
1 | 6130 | 16.3 | 78 | 99.7 | 99.4 |
2 | 6836 | 14.6 | 94 | 99.7 | 99.9 |
3 | 6764 | 14.8 | 97 | 99.8 | 99.9 |
4 | 25,890 | 11.6 | 98 | 98.9 | 99.9 |