From: Optimization of 177Lu-labelling of DOTA-TOC, PSMA-I&T and FAPI-46 for clinical application
Charité | Iori et al. (Iori et al. 2017) | |
---|---|---|
Reaction temperature (°C) | 95 | 90 |
Reaction time (min) | 30 | 30 |
RCY (%) | 93.4 ± 3.9 | 83.1 ± 5.7 |
RCP (%) radio-HPLC | 99.7 ± 0.2 | 99.3 |
RCP (%) TLC | 99.7 ± 0.3 | 98.4 |
amount of DOTA-TOC (µg/GBq) | 10.0–17.0 | 11 |