Table 1 Results of [177Lu]Lu-DOTA-TOC
From: Optimization of 177Lu-labelling of DOTA-TOC, PSMA-I&T and FAPI-46 for clinical application
Synthesis no | Starting activity (MBq) | Amount of DOTA-TOC (µg/GBq) | Balanced radiochem. yield (%) | Radiochem. purity (%) radio-HPLC | Radiochem. purity (%) TLC |
|---|---|---|---|---|---|
1 | 7478 | 15.4 | 92 | 99.8 | 99.9 |
2 | 8485 | 16.7 | 89 | 99.7 | 99.9 |
3 | 8561 | 16.4 | 91 | 99.6 | 99.9 |
4 | 20,270 | 17.0 | 98 | 99.6 | 99.8 |
5 | 5806 | 10.0 | 97 | 99.9 | 99.2 |