Fig. 1

Representative Chromatograms for PSMA I&T. Left: Method A, right: Method B, From top to bottom: I-Radiochromatogram of a test sample of [¹⁷⁷Lu]Lu-PSMA I&T with a radiochemical purity of about 96%; II- ~ 20 × Zoom of radiochromatogram of test sample of [¹⁷⁷Lu]Lu-PSMA I&T; III-20 × zoom of radiochromatogram of test sample of [¹⁷⁷Lu]Lu-PSMA I&T stored at RT for 48 h; IV-UV trace of PSMA I&T standard 200 nm, V-UV trace of a mixture of PSMA I&T and ^natLu-PSMA I&T UV 200 nm; VI- UV-chromatogram of a test sample of [¹⁷⁷Lu]Lu-PSMA I&T. Peak labels: 1: main radiochemical impurity; 2: [¹⁷⁷Lu]Lu-PSMA I&T; 3: PSMA I&T; 4: ^natLu-PSMA I&T