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Table 2 Produced activities at end of synthesis (EOS, not decay corrected) and associated AMA and purities for [68Ga]Ga-PSMA-11 and [68Ga]Ga-DOTATATE. n: Amount of peptide used for radiolabelling. TLC and TLC (colloid) denominates the RCP of [68Ga]Ga-PSMA-11 from analysis for free and colloid gallium-68, respectively

From: Multi-curie production of gallium-68 on a biomedical cyclotron and automated radiolabelling of PSMA-11 and DOTATATE

[68Ga]Ga-PSMA-11
Activity at EOS n AMA at EOS RCP (HPLC) TLC TLC (colloid)
GBq nmol MBq/nmol % % %
39.8 100 398 99.9 100 99.7
42.9 100 429 99.8 100 99.9
72.2 100 722 98.2 100 99.8
   Average: 99.3 100 99.8
   Std.dev.: 1.0 0 0.1
[68Ga]Ga-DOTATATE
Activity at EOS n AMA at EOS RCP (HPLC) ITLC
GBq nmol MBq/nmol % %
0.87 34.8 (50 µg) 25 97.3 98.4
0.88 34.8 (50 µg) 25 98.2 98.4
0.75 34.8 (50 µg) 23 99.7 99.6
3.22 348 (500 µg) 9.2 95.4 97.1
   Average: 97.7 98.4
   Std.dev.: 2.2 1.2