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Table 3 Comparison of requirements for [6xCu]CuCl2 separation vs. other recent literature [reagents for target preparation and recycling not considered]

From: Automated, cassette-based isolation and formulation of high-purity [61Cu]CuCl2 from solid Ni targets

  This study (Ohya et al. 2016, 2019) (Matarrese et al. 2010) (Jalilian et al. 2007) (Strangis and Lepera 2007) (Thieme et al. 2012)
Product isotope 61Cu 64Cu 60/64Cu 64Cu 61Cu 64Cu
Starting material natNi 64Ni 60/64Ni 68Zn natNi 64Ni
Automated Yes Yes Yes No b Partial Partial
Disposable cassette-based purification Yes No No No No No
Prep. Time <  1 h 1 day - a - a - a - a
Process time (min) 65 ± 3 ~  150 ≥ 42 b 105 90–120 ~  200
Total process acid consumption 160 mmol >  200 mmol 460 mmol >  1000 mmol - a >  85 b
Organics No Acetone No No No No
Radiochemical yield (%) 90.4 ± 3.2 88 ± 3 95 95 25–48 >  90
Formulation as stated 2 mL, <  0.1 M HCl Evaporated then reconstituted in ≥10 mL UPW 10 mL, 0.5 M HCl 50 mL, 2 M HCl - a Evaporated then reconstituted in 0.4 mL, 0.01 M HCl
  1. acould not be determined from article
  2. bnot explicitly stated, assumed from context