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EJNMMI Radiopharmacy and Chemistry

Table 1 High level schemes of [68Ga]GaCl3 purifications

From: Cyclotron-based production of 68Ga, [68Ga]GaCl3, and [68Ga]Ga-PSMA-11 from a liquid target

 

Scheme A*

Scheme B

ZR Load

< 0.1 M HNO3

ZR Wash

15 mL 0.1 M HNO3

ZR Elution / Trapping on TK200

5–6 mL ~ 1.75 M HCl

TK Wash

–

3.5 mL 2.0 M NaCl in 0.13 M HCl

TK Elution

H2O

1–2 mL H2O followed by dilute HCl to formulate

  1. *Process as reported previously (Nair et al. 2017)
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