From: Imaging using radiolabelled targeted proteins: radioimmunodetection and beyond
Tracer | Time (h) | Tumor uptake (%ID/g) | Tumor-to-blood ratio | Tumor-to-liver ratio | Tumor-to-bone ratio | Reference |
---|---|---|---|---|---|---|
[89Zr]Zr-DFO- cetuximab | 96 | ~ 4 | ~ 1.5 | ~ 0.3 | Aerts et al. 2009 | |
[86Y]Y-CHX-A”-DTPA-panitumumab | 72 | 23±3 | ~ 3 | ~ 2 | 6-7 | Nayak et al. 2010 |
[57Co]Co- DOTA-ZEGFR:2377 | 3 | 5.8±2.4 | 12±2 | 3.1±0.5 | 24±5 | Garousi et al. 2017b |
[57Co]Co- DOTA-ZEGFR:2377 | 24 | 4.04±0.03 | 32±7 | 3.3±0.3 | 21±5 | Garousi et al. 2017b |
[68Ga]Ga-DOTA-ZEGFR:2377 | 3 | 2.7 ± 0.1 | 7±2 | 0.44±0.03 | 12±2 | Garousi et al. 2017b |
[68Ga]Ga-DFO-ZEGFR:2377 | 3 | 8.6±2.4 | 6.7±2.9 | 2.2±0.8 | 16±5 |