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Table 2 Stability of the radiopharmaceutical in human plasma and in the final formulation up to 4 hs

From: Synthesis of an Al18F radiofluorinated GLU-UREA-LYS(AHX)-HBED-CC PSMA ligand in an automated synthesis platform

Time (post synthesis) (hours) Radiochemical purity in the final formulation at room temperature (%) (n = 3) Radiochemical purity in human plasma at 37 °C (%) (n = 3)
1 94.6 ± 1.8 91.0 ± 0.8
2 92.8 ± 2.5 65.3 ± 3.2
3 93.7 ± 2.0 35.4 ± 1.9
4 94.2 ± 2.8 22.3 ± 2.6