Production of novel diagnostic radionuclides in small medical cyclotrons

EJNMMI Radiopharmacy and Chemistry

Table 4 Comparison of the properties of presented radionuclides

Radionuclide (in order of appearance)	Imaging procedure	T_1/2	I	E_γ or E_{av. β} (keV)	Feasible SMC (< 20 MeV) nuclear reaction	Target type	Yield
^99mTc	SPECT	6.43 h	γ 99%	140.5	¹⁰⁰Mo(p,2n)^99mTc	Solid	513 MBq/μAh(Benard et al., 2014)
¹²³I	SPECT	13.2 h	γ 83%	158	¹²³Te(p,n)¹²³I	Solid	No data
¹²⁴I	PET	4.18 d	β⁺ 12% β⁺ 11% γ 63%	687 975 603	¹²⁴Te(p,n)¹²⁴I	Solid	21 MBq/μAh (Braghirolli et al., 2014)
⁸⁹Zr	PET	78.4 h	β⁺ 23% γ 99%	396 909	⁸⁹Y(p,n)⁸⁹Zr	Solid Liquid	49 MBq/μAh (Siikanen et al., 2014) 4.4 MBq/μAh (Pandey et al., 2016)
⁶⁴Cu	PET	12.7 h	β⁺ 18% β⁻ 39% γ 0.5%	278 190 134	⁶⁴Ni(p,n)⁶⁴Cu	Solid Liquid	304 MBq/μAh (Qaim, 2017) 0.14 MBq/(μAh·mg) (Alves et al., 2017)
⁶⁸Ga	PET	67.7 min	β⁺ 88% γ 3%	836 1077	⁶⁸Zn(p,n)⁶⁸Ga	Solid Liquid	No data 1.5 MBq/(μAh·mg) (Alves et al., 2017)
⁶⁷Ga	SPECT	78.3 h	γ 39% γ 21% γ 17%	93 185 300	⁶⁸Zn(p,2n)⁶⁷Ga ⁶⁷Zn(p,n)⁶⁷Ga	Solid	No data
¹¹¹In	SPECT	67.3 h	γ 94% γ 91%	245 171	¹¹¹Cd(p,n)¹¹¹In	Solid	67.5 MBq/μAh (Alipoor et al., 2011)
⁸⁶Y	PET	14.7 h	β⁺ 12% β⁺ 6% γ 83%	535 681 1077	⁸⁶Sr(p,n)⁸⁶Y	Solid Liquid	166 MBq/μAh (Yoo et al., 2005) 1.44 MBq/μAh (Oehlke et al., 2015)
⁴⁴Sc	PET	3.97 h	β⁺ 94% γ 100%	632 1157	⁴⁴Ca(p,n)⁴⁴Sc	Solid Liquid	25 MBq/μAh (Meulen et al., 2015) 1.4 MBq/μAh (Hoehr et al., 2014)