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Fig. 4 | EJNMMI Radiopharmacy and Chemistry

Fig. 4

From: Expanding a peptide-covalent probe hybrid for PET imaging of S. aureus driven focal infections

Fig. 4

Toxicity of AcCys-2-APBA, UBI and UBI-APBA conjugate against human erythrocytes and HEK 293 cells. a. Bar graphs showing % haemolysis caused by indicated concentrations of AcCys-2-APBA, UBI and UBI-APBA. Untreated erythrocytes were used as negative control (Neg. Ctrl.), whereas Triton-X-100 (0.1%) and melittin (17 µM) treated cells were used as positive controls (Pos. Ctrl.) b. Cell cytotoxicity of UBI and APBA conjugate toward HEK 293 cells *indicates p < 0.05, whereas ***indicates p < 0.0005 (n = 3)

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