Fig. 10
From: Expanding a peptide-covalent probe hybrid for PET imaging of S. aureus driven focal infections
In vivo studies in rat model of S. aureus infection. a Ex-vivo biodistribution of [68Ga] Ga-UBI complexes in rat model of infection and inflammation. b Bar graph comparing the efficacy of in vivo detection of S. aureus by 68Ga tracers. T = % ID/gm at the target or site of infection, B = Blood, NT = non-target or site of sterile inflammation, NM = Normal muscle. c Bar graph showing % excreted activity at 1 h post injection (p.i.) for respective [68Ga]Ga-UBI complexes. d PET images showing accumulation of tracer at the site of infection (white arrow, right thigh muscle) in rat model of infection and no accumulation in sterile inflammation (left thigh muscle), images show renal clearance through kidneys and bladder. *Indicates a p value of < 0.05 (n = 4), NS denotes non-significant difference