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Fig. 5 | EJNMMI Radiopharmacy and Chemistry

Fig. 5

From: Preclinical comparison of [177Lu]Lu-rhPSMA-10.1 and [177Lu]Lu-rhPSMA-10.2 for endoradiotherapy of prostate cancer: biodistribution and dosimetry studies

Fig. 5

Time activity curves of [177Lu]Lu-rhPSMA-10.1 (solid line) and -10.2 (dashed line), expressed as a percentage of the injected dose per gram (%ID/g) between 1 and 168 h p.i. in A in kidneys (blue), spleen (green) and liver (red) of non-tumor bearing mice and B in kidneys (blue), liver (red) and tumor (black) of mice bearing LNCaP tumors. C Tumor uptake (%ID/g) of [177Lu]Lu-rhPSMA-10.1 (black) and -10.2 (grey) at 1, 24 and 168 h and determination of respective tumor-to-kidney ratios (D)

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