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Table 1 Average labeling yield and in vitro stability tests in PBS and EDTA

From: Preclinical evaluation of new GRPR-antagonists with improved metabolic stability for radiotheranostic use in oncology

[111In]In-AU-SAR-

M1

M2

M3

Average yield (%)

97.4 ± 2.6 (n = 7)

98.2 ± 1.8 (n = 5)

97.0 ± 3.0 (n = 6)

tR (min)

10.3

10

9.6

PBS

95.3 ± 1.3%

99.0 ± 0.5%

95.1 ± 1.7%

EDTA

96.4 ± 0.5%

98.1 ± 0.1%

91.4 ± 0.7%

p-value (PBS-EDTA)

0.28

0.03

0.02

  1. Data presented as net % sum area ± sd analysed by iTLC. Significance of difference between PBS and EDTA incubation presented with p-value