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EJNMMI Radiopharmacy and Chemistry
Fig. 2 | EJNMMI Radiopharmacy and Chemistry

Fig. 2

From: Unnatural amino acid substitutions to improve in vivo stability and tumor uptake of 68Ga-labeled GRPR-targeted TacBOMB2 derivatives for cancer imaging with positron emission tomography

Fig. 2

Chemical structures and GRPR binding affinities (Ki, mean ± SD, n = 3) of A Ga-TacBOMB2 and its derivatives with an unnatural amino acid substitution at B His12, C Val10, D Trp8, E Val10 and His12, F Gln7, Val10 and His12, G Gln7, Val10, Gly11 and His12, and H Trp8, Val10 and His12

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