Fig. 10From: Implementing Ac-225 labelled radiopharmaceuticals: practical considerations and (pre-)clinical perspectivesLabelling with a high RCY was injected onto the HPLC (a) and a chromatogram of [225Ac]Ac-PSMA-I&T was obtained, based on indirect Fr-221 measurements. A low RCP labelling (< 60%), showing radiolysis in fractions 5–15. The chromatogram was identical after labelling was SPE Seppak purified and reinjected, confirmed that the peak at fraction 5–15 is still there and thus contain an Ac-225 labelled radiolysed product (b)Back to article page