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Table 2 The range of parameter values utilized for evaluating the effect of injection profile (multi-bolus injection)

From: Physiologically based radiopharmacokinetic (PBRPK) modeling to simulate and analyze radiopharmaceutical therapies: studies of non-linearities, multi-bolus injections, and albumin binding

Parameter

Range of values

Unit

Number of injections

{1,2,3,4,5,6,7,8,9,10}

Dimensionless

Time between injections

{10,50,100,200,300,400,500,750,1000}

min

Tumor receptor density

10 linear samples from the interval [43,342]

nmol/lit

Tumor volume

10 linear samples from the interval [40,2100]

ml

Injection coefficient

{1,2,3,4,5,6}

Dimensionless