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EJNMMI Radiopharmacy and Chemistry
Fig. 5 | EJNMMI Radiopharmacy and Chemistry

Fig. 5

From: Physiologically based radiopharmacokinetic (PBRPK) modeling to simulate and analyze radiopharmaceutical therapies: studies of non-linearities, multi-bolus injections, and albumin binding

Fig. 5

The effect of the tumor volume on the competition degree (i.e. twist) between hot and cold species (tumor receptor density set to 40 nmol/lit). Higher tumor volume does not alter competition in tumor as much as Fig. 4 (changing tumor receptor density), but more greatly impacts competition in kidney and salivary glands due to the tumor sink effect

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