Fig. 11

Hematological analysis and H&E staining. A Hematological analysis showed that the WBC, RBC, HGB, MCH, and PLT counts of low- and high-dose and NY003-only groups decreased within the observation period (14 d p.i.). B The H&E staining results showed regional or focal necrosis within the tumors in low- and high-dose groups, especially the high-dose group, illustrating the therapeutic effect of [¹⁷⁷Lu]Lu-DTPA-NY003. Hepatic congestion and splenic white pulp atrophy were observed in low- and high-dose and NY003-only groups