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EJNMMI Radiopharmacy and Chemistry
Fig. 3 | EJNMMI Radiopharmacy and Chemistry

Fig. 3

From: Intranasal administration enhances size-dependent pulmonary phagocytic uptake of poly(lactic-co-glycolic acid) nanoparticles

Fig. 3

Biodistribution of 89Zr-PLGA-NH2 nanoparticles (900 nm) in mice. Representative coronal and axial PET images at 1, 12, 48, 120, and 144 h after a intravenous and b intranasal nanoparticle administrations. Nanoparticle uptake by major organs presented as %ID/g at 1, 6, 12, 24, 48, 72, 120, and 144 h following c intravenous and d intranasal administrations. Data are presented as mean ± SEM (n = 5). 89Zr-PLGA: radiolabelled poly(lactic-co-glycolic acid); ID: injected dose; PET: positron emission tomography; SEM: standard error of mean

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