Dosimetry of [18F]TRACK, the first PET tracer for imaging of TrkB/C receptors in humans

EJNMMI Radiopharmacy and Chemistry

Table 3 Detriment weighted (E_DW) and effective (E) dose coefficients

Subject	E_DW [mSv/MBq]	σ E_DW	E [mSv/MBq]	σ E	% Activity accounted for	Injeccted Activity [MBq]	Projected E_DW−inj [mSv]	σ E_DW−inj	Projected E_DW−370 [mSv]	σ E_DW−370
S1	0.0154	4.87E−4	0.0170	5.41E−4	91	133	2.26	0.072	6.28	0.200
S2	0.0192	6.12E−4	0.0175	5.57E−4	94	129	2.26	0.072	6.48	0.206
S3	0.0161	4.92E−4	0.0149	4.49E−4	85	156	2.32	0.070	5.51	0.166
S4	0.0177	5.40E−4	0.0164	4.94E−4	92	129	2.12	0.064	6.07	0.183
S5	0.0147	4.54E−4	0.0158	4.95E−4	88	138	2.18	0.068	5.85	0.183
S6	0.0145	3.98E−4	0.0157	4.37E−4	88	147	2.31	0.064	5.81	0.162
Mean and SD	0.0163 ± 1.84E-3		0.0162 ± 0.86E−3		89.7 ± 3.27	138.7 ± 10.86	2.24 ± 0.07		6.00 ± 0.35

E_DW−inj are the estimated detriment weighted doses for each subject’s injected activity, E_DW-370 is an estimated dose for a hypothetical injected activity of 370 MBq