Table 3 Table of cassette design with amounts of reagents
From: Fully automated radiosynthesis of [68Ga]Ga-FAPI-46 with cyclotron produced gallium
Position | Description | Parameter |
|---|---|---|
1 | 14 cm transfer line to the O-18 waste bottle | – |
2 | Precursor vial (11 mm) | 50 μg FAPI-46, 3 mg ascorbic acid, 1.4 mL sodium acetate buffer |
3 | 1 mL syringe | – |
4 | C18 light Sep-Pak with 42 cm transfer line to the central line of the activity receiving vial | Activity receiving vial is connected to the cyclotron transfer line via and to the FASTlab activity inlet line |
5 | 14 cm transfer line to reactor | – |
6 | Conical reservoir (not used) | – |
7 | 14 cm transfer line to reactor | – |
8 | Accell plus CM plus short cartridge with 42 cm transfer line to final filter and final vial | – |
9 | Empty | – |
10 | 42 cm transfer line to 0.9% saline | 50 mL vial of 0.9% saline with spinal needle and vent needle |
11 | 6 mL syringe | – |
12 | Empty | – |
13 | Nitric acid vial (13 mm) | 4 mL 0.6 M HNO3(aq) |
14 | Hydrochloric acid (13 mm) | 4 mL 4 M HCl(aq) |
15 | Sterile water for injection bag | Water spike with 100 mL SWFI bag |
16 | Sodium chloride | 4 mL 3 M NaCl(aq) |
17 | 14 cm transfer line to ZR-Resin | – |
18 | ZR resin cartridge (2 mL) | – |
19 | 42 cm transfer line to zinc waste vial | – |
20 | Anion exchange cartridge | Ag1-X8 resin cartridge, 1 mL resin |
21 | 14 cm transfer line to anion exchange cartridge | – |
22 | TK200 resin cartridge (2 mL) | – |
23 | 14 cm transfer line to TK200 Cartridge | – |
24 | 6 mL syringe | – |
25 | 42 transfer line to reactor | – |