Chelate | Duration of synthesis at RT (min) | Solvent use | Mean RCP (%) | Mean RCP at 24 h (%) | Charge | Log P | Elimination |
---|---|---|---|---|---|---|---|
O-TRENOX (4) | 5 | Ethanol | 98.3 ± 0.2 | 96.0 ± 0.5 | Neutral | 1.2 ± 0.2 Lipophilic | Hepatic and gallbladder |
O-TRENSOX (5) | 5 | Water | 97.6 ± 0.8 | 95.2 ± 0.4 | Negative | − 2.3 ± 0.2 Hydrophilic | Urinary and gallbladder |