From: A simple and efficient automated microvolume radiosynthesis of [18F]Florbetaben
 | Manual Formulationa | Manual Formulationa | Automated Formulation |
---|---|---|---|
Mass of C18 resin in cartridge (mg) | 5 | 10 | 10 |
Number of repeats | n = 1 | n = 3 | n = 3 |
Starting pure [18F]FBB activity (MBq) | 7.4 | 15 ± 11 | 112 ± 51 |
Formulation efficiency (%) | 77 | 91 ± 5 | 81 ± 5 |
Formulation time (min) | 18 | 22 | 17 |
Losses: | |||
 Activity in waste (%) | 19 | 1 ± 1 | 3 ± 3 |
 Fraction collection vial residual activity (%) | 3 | 6 ± 4 | 2 ± 1 |
 Cartridge residual activity (%) | 0 | 0 ± 1 | 1 ± 1 |
 Residual in the system (%) | N/A | N/A | 14 ± 4 |