Table 1 Summary of synthesis performance when performed manually or on the automated setup. All % values are calculated in reference to starting activity.
From: A simple and efficient automated microvolume radiosynthesis of [18F]Florbetaben
| Â | Manual Synthesis | Automated Synthesis |
|---|---|---|
n = 3 | n = 3 | |
Starting activity (MBq) | 260 ± 100 | 330 ± 120 |
Collection efficiency (%) | 87 ± 1 | 83 ± 3 |
Residual chip activity (%) | 0.4 ± 0.2 | 1.2 ± 0.3 |
Radiochemical conversion of the crude (%) | 88 ± 6 | 72 ± 4 |
Crude [18F]FBB yield (%) | 78 ± 6 | 60 ± 5 |
Crude synthesis time (min) | 30 ± 8 | 28 ± 1 |
Isolated [18F]FBB yield (%) | 61 ± 2 | 53 ± 8 |
Molar activity d.c.a (GBq/μmol) | 370 ± 60 | 260 ± 80 |