Table 3 Radiolabelling data for [177Lu]Lu-AAZTA5 and [177Lu]Lu-AAZTA5-TOC
From: AAZTA5/AAZTA5-TOC: synthesis and radiochemical evaluation with 68Ga, 44Sc and 177Lu
177Lu-Radiolabelling | ||||
|---|---|---|---|---|
pH | 4.5 | 5.5 | ||
ligand: Lu ratio | AAZTA5 | AAZTA5-TOC | AAZTA5 | AAZTA5-TOC |
5: 1 | 97.9 ± 1.6 | 98.9 ± 0.5 | 99.9 ± 0.2 | 97.7 ± 1.5 |
10: 1 | 98.6 ± 0.8 | 98.7 ± 1.1 | 99.3 ± 0.7 | 99.6 ± 0.1 |