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Table 1 Reaction conditions of standardized labelling for qualification of equipment

From: Radiolabeling and quality control of therapeutic radiopharmaceuticals: optimization, clinical implementation and comparison of radio-TLC/HPLC analysis, demonstrated by [177Lu]Lu-PSMA

Reaction component

Amount/final concentration

During labelling

[177Lu]LuCl3

74 MBq

PSMA-I&T

7.5 µg

Gentisic acid

5 mM

Ascorbic acid

5 mM

Sodium Acetate

0.025 nM

Directly after labelling

Ethanol (96%)

10% (v/v)

DTPA

2 mM

Final volume (Adjusted with MilliQ)

100 µL