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Fig. 8 | EJNMMI Radiopharmacy and Chemistry

Fig. 8

From: Highlight selection of radiochemistry and radiopharmacy developments by editorial board

Fig. 8

(a) Cellular uptake of [177Lu]Lu-DOTA-TATE (50 kBq) for 1 h in HEKsst2 and PC3 cells and (b) 24 h. Before uptake analysis both cell lines were pretreated with 5-aza-dC and VPA over a time period of 5 days as described above. Unstimulated controls (con) were simultaneously incubated with [177Lu]Lu-DOTA-TATE. The intracellular activity is normalized to results in unstimulated control cells. Results are expressed as changes in percentage in relation to results without stimulation. All data are shown as mean ± SD. The figure is reproduced with permission (Kotzerke et al. 2022)

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