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Table 1 Overview of impurities removed at each SPE-purification step

From: A new automated and putatively versatile synthesis of the PSMA-ligand derivative [18F]DCFPyL using the FASTlabTM synthesizer

Entrya

Purification cartridge

Impurities removed by cartridge

i

Sep-Pak light cartridge

[18F]Fluoride, unreacted F-Py-TFP precursor, and hydrolyzed F-Py-TFP precursor

ii

HILIC cartridge

Unreacted [18F]F-Py-TFP,

iii

Oasis HLB PRiME cartridge

  1. a Based on synthetic scheme numbering (i, ii, iii) in Fig. 3