Fig. 1
From: A proof-of-concept study on the use of a fluorescein-based 18F-tracer for pretargeted PET
Immuno-PET pretargeting approach using fluorescein-based tracers. A bispecific antibody (containing two different scFv antibody fragments) is administered and allowed to circulate for 1–2 days for optimal biodistribution. Then, a labelled fluorescein-based 18F PET-tracer is administered, followed by PET data acquisition