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Table 2 Results from the primary literature study and relevant references

From: Stability evaluation of [18F]FDG: literature study, stability studies from two different PET centres and future recommendations

Study

Year

Title

Relevant references

References

Ferreira

2009

Stability study of 2-[18F]fluoro-2-deoxy-D-glucose ([18F]FDG) stored at room temperature by physicochemical and microbiological assays

Fawdry (2007)

Ferreira et al. (2009)

Hjelstuen

2011

Standardization of fluorine-18 manufacturing processes: New scientific challenges for PET

Jacobson et al. (2009)

Hjelstuen et al. (2011)

Walters

2011

Stability evaluation of [18F]FDG at high radioactive Concentrations

Jacobson et al. (2009), Fawdry (2007), Yu (2006)

Walters et al. (2011)

Dantas

2013

Radiolysis of 2-[18F]fluoro-2-deoxy-D-glucose ([18F]FDG) and the role of ethanol, radioactive concentration and temperature of storage

Jacobson et al. (2009)

Dantas et al. (2013)

Rahmani

2017

Synthesis, quality control and stability studies of 2-[18F]Fluoro-2-Deoxy-D-Glucose(18F-FDG) at different conditions of temperature by physicochemical and microbiological assays

Hamacher et al. (1986), Hung (2002), Fawdry (2007), Ferreira et al. (2009), Yu (2006)

Rahmani et al. (2017)

Joszai

2019

Recommendations for selection of additives for stabilization of [18F]FDG

Hamacher et al. (1986), Dantas et al. (2013), Meyer et al. (1999), Fawdry (2007), Jacobson et al. (2009), Rensch et al. (2012), Kiselev et al. (2006), Mosdzianowski et al. (2002)

Jószai et al. (2019)

Hamacher

1986

Efficient stereospecific synthesis of no-carrier-added 2-[18F]-Fluoro-2-Deoxy-D-Glucose using aminopolyether supported nucleophilic substitution

 

Hamacher et al. (1986)

Meyer

1999

The stability of 2-[18F]fluoro-2-deoxy-D-glucose towards epimerisation under alkaline conditions

 

Meyer et al. (1999)

Hung

2002

Comparison of various requirements of the quality assurance procedures for [18F]FDG injection.

 

Hung (2002)

Kiselev

2002

Stabilization of radiopharmaceuticals labelled with [18F]fluoride. US Patent

 

Kiselev et al. (2006)

Mosdzianowski

2002

Epimerization study on [18F]FDG produced by an alkaline hydrolysis on solid support under stringent conditions

 

Mosdzianowski et al. (2002)

Yu

2006

Review of [18F]FDG synthesis and quality control

 

Yu (2006)

Fawdry

2007

Radiolysis of 2-[18F]fluoro-2-deoxy-D-glucose ([18F]FDG) and the role of reductant stabilisers

 

Fawdry (2007)

Jacobson

2009

Radiolysis of 2-[18F]fluoro-2-deoxy-D-glucose([18F]FDG) and the role of ethanol and radioactive concentration

 

Jacobson et al. (2009)

Rensch

2012

Microfluidic reactor geometries for radiolysis reduction in radiopharmaceuticals

 

Rensch et al. (2012)

Long

2013

Comparison of FASTlab [18F]FDG production using phosphate and citrate buffer cassettes

 

Long et al. (2013)