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Table 1 Reaction conditions for radiolabeling

From: A suitable time point for quantifying the radiochemical purity of 225Ac-labeled radiopharmaceuticals

Compound

Chelator

[Compound] (μM)

T (°C)

RPS-072

DOTA

9.0

95

RPS-074

Macropa

8.9

25

0.89

0.089

RPS-088

Macropa

10.4

25

1.04

0.104

RPS-092

Macropa

8.4

25

0.84

EuK-106

DOTA-106

18.2

95

EuK-107

DOTA-107

20.0

95

  1. Conditions were selected to increase diversity rather than to maximize radiochemical yield. The chelator associated with each molecule is indicated. Full structures are provided in Additional file 1: Fig. S1