Safe use of radiopharmaceuticals in patients with chronic kidney disease: a systematic review

EJNMMI Radiopharmacy and Chemistry

Table 5 Newcastle–Ottawa Scale assessment for cohort studies (Ottawa Hospital Research Institute 2019; Singh et al. 2015)

Study	Selection				Comparability		Outcome			Total score
Study	Representativeness of the exposed cohort	Selection of the non-exposed cohort	Ascertainment of exposure	Demonstration that outcome of interest was not present at start of study	Comparability of cohorts on the basis of the design or analysis	Study controls for any additional factor	Assessment of outcome	Follow-up long enough for outcomes to occur	Adequacy of follow-up of cohorts	Total score
Akers et al. (2016)	*	*	0	0	0	0	0	*	*	4
Minamimoto et al. (2007)	*	*	0	*	*	0	0	*	*	6

'*' means one awarded point
Good-quality: awarded 3–4 stars in the selection domain and 1–2 stars in the comparability domain and 2 stars in the outcome domain. Fair studies: awarded 2 stars for selection and 1–2 stars for comparability and 1–2 stars for outcome. Poor-quality: awarded 0–1 stars for selection or 0 for comparability or 0 for outcome (Singh et al. 2015)