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Fig. 9 | EJNMMI Radiopharmacy and Chemistry

Fig. 9

From: Closing the gap between 19F and 18F chemistry

Fig. 9

A Radiosynthesis of [18F]ArOCF3, [18F]ArOCF2H, and [18F]ArSCF3 by Ag-mediated halogen exchange with [18F]fluoride. B [18F]trifluoromethylthiolation with difluorocarbene precursors and [18F]fluoride. C Radiosynthesis of [18F]ArSCF3 from aryl boronic esters. D Radiosynthesis of [18F]ArSCHF2 from aryl boronic acids. E Synthesis of N-CF3 and N-CF2H. EWG = electron-withdrawing group, EDG = electron-donating group

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