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EJNMMI Radiopharmacy and Chemistry
Fig. 3 | EJNMMI Radiopharmacy and Chemistry

Fig. 3

From: Closing the gap between 19F and 18F chemistry

Fig. 3

A Balz-Schiemann reaction. B Nucleophilic aromatic substitution with [18F]F−. C Microwave-assisted radiofluorination of m-substituted arene precursors. D Radiofluorination of sydnones. E Reactions of [18F]F− with diaryliodonium salts affording electron-rich aryl [18F]fluoride. F Reactions of [18F]F− with diaryliodonium salts bearing 2-thienyl group. G Radiofluorination of spirocyclic hypervalent iodine(III) precursors for non-activated and hindered arenes. EWG = electron-withdrawing group. EDG = electron-donating group. LG = leaving group

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