Skip to main content

Table 1 Examples of [18F]F purification by QMA SPE cartridge

From: The aluminium-[18F]fluoride revolution: simple radiochemistry with a big impact for radiolabelled biomolecules

  Cartridge Wash Eluent References
1 Sep-Pak light QMA 0.9% NaCl (1 mL) Jiang et al. (2021)
2 Sep-Pak Accell Plus QMA Water (5 mL) 0.05 M NaOAc, pH 4.5 (300 µL) Lütje et al. (2019)
3 Sep-Pak light QMA Water 0.5 M NaOAc, pH 4.5 (500 µL) Giglio et al. (2018)
4 Sep-Pak Accell Plus QMA Purged to dryness 0.5 M NaHCO3 or NaNO3 or NaCl or NaOAc (600 µL) Kersemans et al. (2018)
5 Sep-Pak Accell Plus QMA light Water (6 mL) 0.9% NaCl (250 µL) Tshibangu et al. (2020)
  1. Elution of [18F]F from a QMA is invariably efficient (ca. 99% recovery) but the choice of eluent can modulate radioactive concentration. This was demonstrated by Kersemans et al. (2018) and may be considered as a parameter for optimisation when developing new [18F]AlF labelling protocols (Kersemans et al. 2018)