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Table 1 Characteristics of the 1-step synthesis performed in Eckert & Ziegler and IBA Synthera. Values reported in mean ± SD

From: A new approach to produce [18F]MC225 via one-step synthesis, a PET radiotracer for measuring P-gp function

Procedure

Total Reaction time (min)

Drying time (min)

RCY (%)

% Area[18F]MC225 (UPLC)

Molar Activity (Am) (GBq/ mmol)

Eckert & Ziegler

(n = 9)

120.44 ± 26.33

20.33 ± 5.89

3.76 ± 2

91.70 ± 3.8

>  100,000

IBA synthera

(n = 9)

106.09 ± 13.06

10.44 ± 0.73

6.53 ± 3

97.14 ± 1.12

>  100,000