Starting material | Separation Method | Reference |
---|---|---|
TiO2 | ion exchange the AG MP-500 (Bio-Rad) was used after a preliminary treatment in 5 M HNO3 and rinsing with H2O. Ti(IV) was poorly sorbed. Subsequently, scandium was eluted using ammonium acetate | (Pietrelli et al. 1992) |
solvent extraction tri-n-butylphosphate (TBP) was used with an equal volume of 8 N HCl, washed with H2O and a 6% of carbonate solution. Equal volumes of aqueous phase of ion solution and TBP were used. Cupferron (ammonium salt of the conjugate base derived from N-nitroso-N-phenylhydroxylamine) was also used and Ti(IV) was extracted as cupferrate by 100% chloroform, Sc was separated from Ti by “gravity” with 98% of Sc extracted | ||
extraction chromatography tri-n-butylphosphate (TBP) was used with an equal volume of 8 N HCl, washed with H2O and a 6% of carbonate solution. Equal volumes of the aqueous phase of ion solution and TBP were used. TBP sorbed onto silica showed that 97.7% of Sc(III) were eluted with 2 mL of HCl 0.1 N. No titanium was detected in the final samples | (Pietrelli et al. 1992) | |
extraction chromatography DGA resin could be used for Ti/Sc trace separations in the context of a fine purification of 44Ti from the residual scandium target material. By contrast, ZR® resin was shown to exhibit a high sorption affinity for titanium, whereas scandium could be eluted with HCl solutions. Nonetheless, there are some drawbacks concerning this generator since some breakthrough of 44Ti has been observed after several bed elutions. | (Majkowska-Pilip and Bilewicz 2011) | |
Ti(0) | extraction chromatography Dissolution in NH4HF2 Elution on a branched DGA resin, recovery of scandium 88% | |
CaCO3 | extraction chromatography target dissolved in HCl solution, passed through a UTEVA® resin column and the column washed with HCl. The scandium radionuclides were eluted with H2O. Efficiency 80% | |
extraction chromatography dissolving the CaCO3 targets in HCl solution, passed through a DGA® resin with HCl. Afterwards, the acidic 47Sc solution was passed throught SCX cation exchange cartridges cation and eluted with HCl. Efficiency 93% | (Domnanich et al. 2017a) | |
extraction chromatography dissolving the CaCO3 targets in HCl solution, passed through a DGA® resin with HCl. Afterwards, the acidic 43Sc or 44Sc solution was loaded on a column filled with DOWEX50 cation exchange resin and 43Sc or 44Sc was eluted using ammonium acetate solution at pH = 4. Efficiency 75% | (van der Meulen et al. 2015; Muller et al. 2014; van der Meulen et al. 2020) | |
Ion exchange dissolution of the target in HCl and adsorption of 43Sc or 44Sc and even 47Sc onto a chelating ion exchange resin Chelex 100. After adsorption of Sc, the column was washed with 0.01 M HCl to remove Ca2+, scandium was eluted with 1 M HCl. Efficiency 70% | (Walczak et al. 2015; Krajewski et al. 2013; Gizawy et al. 2020) | |
extraction chromatography loading the dissolved target acidic solution onto DGA®; rinsed in 4 M HCl; HCl was then necessary to elute quantitatively scandium from the DGA® resin. Efficiency 95% | (Chaple and Lapi 2018; Alliot et al., 2015a; Filosofov et al. 2010) | |
extraction chromatography dissolution of the target in 9 M HCl, loaded on TBP resin column, 47Sc eluted with H2O. Than loaded onto a BioRad AG50WX4 resin, washed with HCl 0.1 M and H2O; 47Sc was eluted with portions of 1 M sodium acetate solution at pH 4.5. Separation yield 52–79% | (Rotsch et al. 2018) | |
extraction chromatography target dissolved in 11 M HCl solution, passed through a UTEVA® resin column. Scandium radionuclides were eluted with H2O and loaded on a BioRad AG50WX4 resin, washed with HCl 0.1 M and 44Sc was eluted with portions of 1 M sodium acetate solution at pH 4.5 Separation yield 93.5% | (Muller et al. 2018) | |
extraction chromatography dissolution of the target in 1 mL 2 M HCl, partial neutralization with 0.7 mL 1 M NaOH, pH adjustment with pH 3 formate buffer loading on Nobias PA-1 (iminobisacetic acid–ethylenediaminetriacetic acid chelate resin) resin column, washing with 2 mL formate buffer, pH 3, elution with 0.1 mL 2 M HCl, separation yield: 95% | (Kilian et al. 2018) | |
Precipitation calcium target dissolved with 2 M HCl, pH adjusted to 6.5–9.0 by addition of 1 M NH4OH, solution pushed through a 0.22 μm Millex-GV 13 mm diameter syringe filter washed with 10 mL 0.1 M NH4OH adjusted to pH 8–9 with HCl. | (Severin et al. 2012) | |
extraction chromatography target dissolved in HCl solution, 44Sc was separated from excess of calcium by precipitation of scandium hydroxide using ammonia. passed through a UTEVA® resin column and the column washed with HCl. The scandium radionuclides were eluted with H2O. Efficiency 80% | (Wojdowska 2019) | |
electroamalgamation selective electroamalgamation of Ca2+ ions | (Chakravarty et al. 2017) | |
precipitation Dissolution of the target in 1 M HCl, then alkalized with 25% ammonia. Method takes advantage of the insolubility of Sc(OH)3 either as a precipitate or coprecipitate, which can be separated from calcium by using microfilters with PTFE membrane (0.22 μm) | (Minegishi et al. 2016; Severin et al. 2012; Duval and Kurbatov 1953) |