Table 4 The final product specifications for [177Lu]Lu-FAPI-04 and [177Lu]Lu-FAPI-46 (n = 3, 100 mCi, [177Lu] Lu & 100 μg of FAPI derivatives)
From: Fully-automated synthesis of 177Lu labelled FAPI derivatives on the module modular lab-Eazy
Test | [177Lu]Lu-FAPI-04 (n = 3) | [177Lu]Lu-FAPI-46 (n = 3) |
|---|---|---|
Radiochemical yield | 88% ± 3 | 86% ± 3 |
Radiochemical purity (R-HPLC) | ≥ %99 | ≥ %99 |
Radiochemical purity (R-TLC) | ≥ %99 | ≥ %99 |
pH | 4,5–8 | 4,5–8 |
Appearance | Clear, Colorless | Light yellow |
Volume | 15–20 mL. | 15–20 mL. |
Radioactivity concentration | 4–6 mCi/ml | 4–6 mCi/ml |